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April 24, 2014

MDMA (ecstasy) MDMA (Methylenedioxy-methamphetamine) is universally known as ecstasy. It is an artificial drug that affects the mind of the user. It has similarities to both its stimulant (amphetamine) and hallucinogen (mescaline). It is used to create stimulated increased in euphoria, energy, emotional warmth and compassion towards others. It also distorts carnal and periodic tempo of the user. MDMA was first seen in affect at nightclubs and “rave parties”. It was commonly abused by white minors and young adults. Today, the drug affects a broader range of people and societies. How can MDMA be abused? Generally, MDMA is orally abused in the form of a tablet or capsule. In minor dosage the effects of this drug last through a period of 3-6 hours. It is not common for users to take a second dosage of MDMA as the first effects start to wear off, commonly taken in combination with other synthetic or natural drugs. For example, some MDMA abusers from the gay fraternity claim that they took the drug as a part of a multiple-drug process that included, GHB, methamphetamine, ketamine, Viagra and Cocaine. Effects of MDMA on the Brain. MDMA affects three neurotransmitters in the brain – Serotonin, dopamine and norepinephrine. Its altruistic and emotional effects are caused directly or indirectly. After intake, there is a release in large amount of serotonin in the brain; this has an influence on the mood of the person. This generally accounts for all the characteristic feelings of emotional longing and intimacy. This abnormal release of serotonin in the brain, reduces the level of this important chemical in the brain hereby causing major after-effects like; confusion, insomnia, drug craving, anxiety and depression. Other Health Effects of MDMA The physical effects of MDMA are similar to that of other illegal stimulants like cocaine and amphetamine. One major effect in health is it gradually increases the heart rate and pressure of the user. If someone already has circulatory or respiratory problems, this can result in instant death of the person. Other common problem faced by MDMA abusers is tension in muscles, involuntary clenching of teeth, blurry vision, nausea, sweating, chill and faintness. If taken in really high dosage, MDMA can have a tremendously adverse effect in the temperature regulation of the body. On rare occasions users can have problems like hyperthermia which can result in liver, kidney or cardiovascular failure. Users who by chance or intentionally abuse MDMA with a combination of other drugs are putting themselves in great danger of called diseases and body symptoms.

MDMA is considered unusual for its tendency to induce a sense of intimacy with others and diminished feelings of fear, anxiety, and depression. MDMA is criminalized in most countries in the world under a United Nations (U.N.) agreement,and its possession, manufacture, or sale may result in criminal prosecution, although some limited exceptions exist for scientific and medical research. MDMA is one of the most widely used recreational drugs in the world and is taken in a variety of contexts far removed from its roots in psychotherapeutic settings. It is commonly associated with dance parties (or "raves") and electronic dance music. Where to buy ecstasy

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There have been debates within scientific, health care, and drug policy circles about the risks of MDMA, specifically the possibility of neurotoxic damage to the central nervous system (CNS). Regulatory authorities in several locations around the world have approved scientific studies administering MDMA to humans to buy xtc examine its therapeutic potential and its effects. MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch. At the time, Merck was interested in developing substances that stopped abnormal bleeding. Merck wanted to evade an existing patent, held by Bayer, for one such compound: hydrastinine. At the behest of his superiors Walther Beckh and Otto Wolfes, Köllisch developed a preparation of a hydrastinine analogue, methylhydrastinine. MDMA was an intermediate compound in the synthesis of methylhydrastinine, and Merck was not interested in its properties at the time. On December 24, 1912 Merck filed two patent applications that described the synthesis of ecstasy and its subsequent conversion to methylhydrastinine. MDMA first appeared as a street drug in the early 1970s after its counterculture analogue, MDA, became criminalized in the United States in 1970. In the mid-1970s, Alexander Shulgin, then at University of California, heard from his students about unusual effects of MDMA; among others, the drug had helped one of them to overcome his stutter. Intrigued, Shulgin synthesized MDMA and tried it himself in 1976. Two years later, he and David Nichols published the first report on the drug's psychotropic effect in humans. Buy ecstasy online

They described "altered state of consciousness with emotional and sensual overtones" that can be compared "to marijuana, to psilocybin devoid of the hallucinatory component" buy ecstasy, buy mdma, buy xtc, buy extasy, buy ecstacy, buying ecstasy, buy xtz] Shulgin took to occasionally using MDMA for relaxation, referring to it as "my low-calorie martini", and giving the drug to his friends, researchers, and other people whom he thought could benefit from it. One such person was psychotherapist Leo Zeff, who had been known to use psychedelics in his practice. Zeff was so impressed with the action of MDMA that he came out of his semi-retirement to proselytize for it. Over the following years, Zeff traveled around the U.S. and occasionally to Europe training other psychotherapists in the use of MDMA. Among underground psychotherapists, MDMA developed a reputation for enhancing communication during clinical sessions, buy mdma psychological defenses, and increasing capacity for therapeutic introspection.

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After MDMA was criminalized, most medical buy xtz use stopped, although some therapists continued to prescribe the drug illegally buy extasy. Later Charles Grob initiated an ascending-dose safety study in healthy volunteers. Subsequent legally-approved MDMA studies in humans have taken place in the U.S. in Detroit (Wayne State University) buy ecstacy, Chicago (University of Chicago), San Francisco (UCSF and California Pacific Medical Center), Baltimore (NIDA-NIH Intramural Program), and South Carolina, as well as in Switzerland (University Hospital of Psychiatry, Zürich), the Netherlands (Maastricht University), and Spain (Universitat Autònoma de Barcelona) buy pure mdma capsules. The primary effects attributable to MDMA consumption are predictable and fairly consistent amongst users. Generally, buy pure mdma capsules users report feeling effects within 30–60 minutes of consumption, hitting a peak at approximately 1–1.5 hours, reaching a plateau that lasts about 2–3 hours,buying ecstasy followed by a comedown of a few hours which may be accompanied by fatigue and minor ecstasy effects Read more >>>

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MDMA has become a popular drug, in part because of the positive effects that a person experiences within an hour or so after taking a single dose. Those effects include feelings of mental stimulation, emotional warmth, empathy toward others, a general sense of well being, and decreased anxiety. In addition, users report enhanced sensory perception as a hallmark of the MDMA experience. Because of the drug's stimulant properties, when used in club or dance settings MDMA can also enable users to dance for extended periods. However, there are some users who report undesirable effects immediately, including anxiety, agitation, and recklessness. As noted, MDMA is not a benign drug. MDMA can produce a variety of adverse health effects, including nausea, chills, sweating, involuntary teeth clenching, muscle cramping, and blurred vision. MDMA overdose can also occur - the symptoms can include high blood pressure, faintness, panic attacks, and in severe cases, a loss of consciousness, and seizures. Because of its stimulant properties and the environment in which it is often taken, MDMA is associated with vigorous physical activity for extended periods. This can lead to one of the most significant, although rare, acute adverse effects -- a marked rise in body temperature (hyperthermia). Treatment of hyperthermia requires prompt medical attention, as it can rapidly lead to muscle breakdown, which can in turn result in kidney failure.

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In addition, dehydration, hypertension, and heart failure may occur in susceptible individuals. MDMA can also reduce the pumping efficiency of the heart, of particular concern during periods of increased physical activity, thereby further complicating these problems. Where to buy ecstasy online

MDMA is rapidly absorbed into the human blood stream, but once in the body MDMA interferes with the body's ability to metabolize, or break down, the drug. As a result, additional doses of MDMA can produce unexpectedly high blood levels, which could worsen the cardiovascular and other toxic effects of this drug. MDMA also interferes with the metabolism of other drugs, including some of the adulterants that may be found in MDMA tablets.

In the hours after taking the drug, MDMA produces significant reductions in mental abilities. These changes, particularly those affecting memory, can last for up to a week, and possibly longer in regular users. The fact that MDMA markedly impairs information processing emphasizes the potential dangers of performing complex or even skilled activities, such as driving a car, while under the influence of this drug.

Over the course of the week following moderate use of the drug, many MDMA users report feeling a range of emotions, including anxiety, restlessness, irritability, and sadness that in some individuals can be as severe as true clinical depression. Similarly, elevated anxiety, impulsiveness, and aggression, as well as sleep disturbances, lack of appetite and reduced interest in and pleasure from sex have been observed in regular MDMA users.

Some of these disturbances may not be directly attributable to MDMA, but may be related to some of the other drugs often used in combination with MDMA, such as cocaine or marijuana, or to potential adulterants found in MDMA tablets.

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